Recombinant human R-Spondin-1 protein

Catalog Number	OGF010
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Introduction

Recombinant human R-Spondin-1 protein is a high-quality recombinant protein produced for research use, supporting cell culture, organoid growth, and in vitro biological studies with reliable activity and consistency.

Background

R-spondin 1 is a secreted protein that potentiates Wnt/β-catenin signaling by stabilizing Frizzled and LRP receptors on the cell surface. It is a critical component in intestinal and epithelial stem cell maintenance and is widely used in organoid cultures to enhance stem cell expansion and viability.

Product Information

Species	Human
Formulation	1x PBS, See Certificate of Analysis for details
Organoid Type	Intestinal Organoids; Esophageal Organoid; Prostate Organoid; Breast organoids
Growth Factor	R-spondin1
GeneID	284654
Expression	HEK293
Activity	4-20 ng/mL
Purity	>95%
Endotoxin	<1 EU/μg
Accession Number	Q2MKA7
Molecular Mass	36-50 kDa reduced and non-reduced, monomer, glycosylated
Species Reactivity	human
Stability and Storage	Lyophilized: Store at −20 °C to −80 °C until expiry date; alternatively, stable at room temperature for up to 2 weeks Reconstituted (per CoA): Stable for up to 6 months at −20 °C to −80 °C, or up to 1 week at 13 °C
Reconstitution	Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap vial to mix.
Synonyms	Roof-plate specific spondin-1, Critsin3, RSPO1,HRspo1

For research use only. Not for any other purpose.

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