Recombinant human Noggin protein

Catalog Number OGF006
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Introduction

Recombinant human Noggin protein is a high-quality recombinant protein produced for research use, supporting cell culture, organoid growth, and in vitro biological studies with reliable activity and consistency.

Background

Noggin is a secreted glycoprotein that functions as a potent inhibitor of bone morphogenetic protein (BMP) signaling. By binding to BMPs such as BMP2 and BMP4, Noggin prevents receptor activation and plays a key role in embryogenesis, neural induction, and the maintenance of stem and progenitor cell populations.

Product Information

Species Human
Formulation 1x PBS, See Certificate of Analysis for details
Organoid Type Retinal Organoids; Lung Organoids; Intestinal Organoids; Gastric Organoids; Pancreatic Organoids; Esophageal Organoid; Prostate Organoid
Growth Factor Noggin
GeneID 9241
Expression HEK293
Activity 1.5-15 ng/mL
Purity >95%
Endotoxin <1 EU/µg
Accession Number Q13253
Molecular Mass 28 kDa reduced, 50 to 95 kDa non-reduced, homodimer, glycosylated
Species Reactivity human,mouse
Stability and Storage
  • Lyophilized: Store at −20 °C to −80 °C until expiry date; alternatively, stable at room temperature for up to 2 weeks
  • Reconstituted (per CoA): Stable for up to 6 months at −20 °C to −80 °C, or up to 1 week at 9 °C
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 1xPBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap vial to mix.
Synonyms NOG, noggin, SYM1, SYNS1
For research use only. Not for any other purpose.

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