Recombinant human GDNF protein

Catalog Number OGF014
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Introduction

Recombinant human GDNF protein is a high-quality recombinant protein produced for research use, supporting cell culture, organoid growth, and in vitro biological studies with reliable activity and consistency.

Background

Glial Cell Line–Derived Neurotrophic Factor (GDNF) supports the survival and differentiation of dopaminergic neurons and other neuronal populations. It is essential for nervous system development and kidney morphogenesis and is extensively used in neurobiology, stem cell research, and neurodegenerative disease models.

Product Information

Species Human
Formulation 1x PBS, See Certificate of Analysis for details
Organoid Type Kidney Organoids; Brain organoids
Growth Factor GDNF
GeneID 2668
Expression HEK293
Activity <10 ng/mL
Specific Activity ≥ 1.00 x 10^6 IU/mg
Purity >95%
Endotoxin <1 EU/μg
Accession Number P39905
Molecular Mass 22 to 25 kDa reduced, 30 to 38 kDa non-reduced, homodimer, glycosylated
Species Reactivity human
Stability and Storage
  • Lyophilized: Store at −20 °C to −80 °C until expiry date; alternatively, stable at room temperature for up to 2 weeks
  • Reconstituted (per CoA): Stable for up to 6 months at −20 °C to −80 °C, or up to 1 week at 17 °C
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap vial to mix.
Synonyms ATF, ATF1, ATF2, GDNF, HFB1 GDNF, hGDNF
For research use only. Not for any other purpose.

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