Recombinant human FGF-4 protein

Catalog Number	OGF024
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Introduction

Recombinant human FGF-4 protein is a recombinant growth factor designed for in vitro research, widely used in cell culture and organoid-related studies to support cell growth and functional analysis.

Background

Fibroblast growth factor 4 (FGF-4) is a member of the FGF superfamily involved in early embryonic development and stem cell regulation. It contributes to cell proliferation, differentiation, and lineage specification.

FGF-4 supports the maintenance and self-renewal of pluripotent stem cells and enhances proliferation of neural stem cells and mesenchymal stem cells. It functions synergistically with WNT signaling in the formation of posterior endoderm and intestinal organoids from pluripotent stem cells.

Recombinant FGF-4 is commonly used in directed differentiation protocols, particularly for modeling early embryonic and intestinal development in vitro.

Product Information

Species	Human
Formulation	1x PBS, See Certificate of Analysis for details
Organoid Type	Lung organoids
Growth Factor	FGF-4
GeneID	2249
Expression	HEK293
Activity	≈1.25 ng/mL
Purity	>95%
Endotoxin	<1 EU/µg
Accession Number	P05230
Molecular Mass	~20 kDa
Species Reactivity	human species similarity: mouse - 91% rat - 80% bovine - 90% porcine - 91%
Stability and Storage	Lyophilized: Store at −20 °C to −80 °C until expiry date; alternatively, stable at room temperature for up to 2 weeks Reconstituted (per CoA): Stable for up to 6 months at −20 °C to −80 °C, or up to 1 week at 27 °C
Reconstitution	Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 1x PBS pH 7.4 containing 0.9% endotoxin-free recombinant serum albumin (HSA). Gently swirl or tap vial to mix.
Synonyms	Fibroblast Growth Factor-4, Kaposi’s sarcoma-associated FGF, k-FGF, Heparin secretory-transforming protein 1 HST-1, Transforming protein KS3, Heparin-binding growth factor 4, HBGF-4, FGF4 FGF 4, Qk4, Qk04

For research use only. Not for any other purpose.

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