Recombinant human DKK-1 protein

Catalog Number OGF005
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Introduction

Recombinant human DKK-1 protein is a high-quality recombinant protein produced for research use, supporting cell culture, organoid growth, and in vitro biological studies with reliable activity and consistency.

Background

Dickkopf-Related Protein 1 (DKK1) is a secreted antagonist of the canonical Wnt/β-catenin signaling pathway. By inhibiting Wnt receptor activation, DKK1 regulates embryonic development, cell fate determination, and tissue patterning, and is widely used to induce differentiation or suppress stemness in developmental and stem cell research.

Product Information

Species Human
Formulation 1x PBS, See Certificate of Analysis for details
Organoid Type Retinal Organoids
Growth Factor DKK1
GeneID 22943
Expression HEK293
Activity 7-70 ng/mL
Purity >95%
Endotoxin <1 EU/µg
Accession Number O94907
Molecular Mass 37-51 kDa reduced, 35-49 non-reduced, monomer, glycosylated
Species Reactivity human
Stability and Storage
  • Lyophilized: Store at −20 °C to −80 °C until expiry date; alternatively, stable at room temperature for up to 2 weeks
  • Reconstituted (per CoA): Stable for up to 6 months at −20 °C to −80 °C, or up to 1 week at 8 °C
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap vial to mix.
Synonyms SK, Dickkopf-1, Dickkopf-related protein-1, mDkk-1
For research use only. Not for any other purpose.

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