Branching Lung Organoid Maturation Kit
| Catalog Number | OCM005 |
| Price | Online Inquiry |
Introduction
A serum-free formulation designed to maintain and mature human branching lung organoids for extended periods exceeding 28 days. This system enables reproducible maturation of lung bud organoids derived from embryonic and induced pluripotent stem cells, resulting in organoids that develop proximal and distal-like branching airway epithelial structures expressing EPCAM, NKX2.1, SOX2, SOX9, MUC1, and P63. Extended culture in matrix sandwich configurations demonstrates increased expression of mature lung cell markers including SFTPC, SFTPB, and ABCA3.
Application
Differentiation, Genome Editing, Organoid Culture
Feature
Drives the acquisition of advanced alveolar and airway cell fates, creating a more physiologically relevant model for adult lung function and disease.
Product Information
| Species | Human |
| Formulation | Serum-Free |
| Cell Type | Epithelial Cells, PSC-Derived, Mesenchymal Cells, PSC-Derived, Pluripotent Stem Cells |
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